Pharmaceutical Grade Exceed 99% purity (natural sources) and contain no binders, fillers, excipients, dyes, or unknown substances. 

B12 (5,000 mcg) & Folate (1,700 mcg) / 1mg as Quatrefolic®

Methyl B12

Sublingual  Methyl B12 includes a concentrated and bioavailable source of two key B  vitamins: B12 and folate. This comprehensive blend helps support  numerous systems in the body. 


$22 Methyl B12 | Sublingual

  • Includes High-Concentration, Fast-Absorbing Bioactive Methylcobalamin and Methylfolate (100% as 5-MTHF)
  • Boosts Energy Levels and Supports Red Blood Cell Production
  • Promotes Cardiovascular Health and Homocysteine Balance
  • Rejuvenates Nerve Cell Function and Boosts Cognitive Health
  • Supports a Positive Mood and Healthy Sleep Cycle Regulation


This formulation of Methyl B12 includes a concentrated and bioavailable source of two key B vitamins: B12 and folate. Each tablet provides 5,000 mcg of methylcobalamin and 1,000  mcg of folate as Quatrefolic® -100% 5-MTHF. This synergistic blend of  methyl-donating B vitamins quickly boosts tissue and brain levels to  support numerous systems in the body. 


Vitamin B12 works along with folate in many body processes,  including increasing metabolic energy and red blood cell production,  supporting mood regulation and cognitive function, up-regulating  methylation, increasing DNA synthesis and repair, and supporting the  formation of the protective myelin sheath, the insulating exterior that  speeds up nerve cell transmission.

Most B12 supplements contain cyanocobalamin. In order for  B12 to be utilized in the body, the liver must first remove the cyanide  molecule and attach a methyl group to form methylcobalamin, the  biologically active, tissue-ready form. Research has shown that  methylcobalamin is more efficiently used and retained in the body than  the cyanocobalamin form.


The body’s cells and organ systems depend on an adequate supply of energy to function optimally

The mitochondria, known as the power house of the cell, contain  nutrients and enzymes that are important for cellular energy metabolism,  including those that convert food to usable energy in the form of  adenosine triphosphate (ATP). ATP functions as the key source of energy  for all cells. In order to increase mitochondrial output, there must be  adequate fuel supply for combustion and abundant antioxidants to  scavenge free radical by-products. Preserving our energy reserves and  increasing energy output is a critical part of maintaining optimal  health.

There are many things that can drain energy reserves. Lack of sleep,  too much stress, poor nutrition, and prescription medications can draw  on our energy reserves using them up faster than they can be  replenished. Even the vital biologic systems relied on to maintain  health can create an energy deficit that needs to be restored.

MitoCORE is scientifically formulated, based on published research, to  boost mitochondrial reserves and jump-start cellular energy production.  MitoCORE includes the powerful antioxidant trio of alpha lipoic acid,  N-acetyl cysteine and acetyl L-carnitine shown to increase energy  production and at the same time, recharge the primary cellular  antioxidant pools of vitamin E, C and glutathione. MitoCORE also  includes key micronutrients and phytonutrients including green tea,  broccoli seed extract and resveratrol to protect the mitochondria and  continually renew the cycle of energy production.


Methylcobalamin | Vitamin B12

Because of its role in the production of cellular energy, vitamin B12 deficiency is often characterized by fatigue and weakness.  Supplementation with methylcobalamin and 5-MTHF has been shown to  promote increased energy levels. Both 5-MTHF and methylcobalamin are  required to maintain optimal homocysteine balance, which is crucial for  supporting arterial and cardiovascular health. In addition, 5-MTHF and  methylcobalamin support healthy arterial blood flow by increasing nitric  oxide production. Both are also required nutrients for the biosynthesis  of melatonin-the hormone that helps induce sleep. Several studies have  demonstrated that supplementation with methylcobalamin modulates  melatonin secretion and helps to normalize the sleep-wake cycle.

Vitamin B12 has been shown to be beneficial for maintaining a  positive mental outlook because it acts as a methyl donor and increases  the synthesis of SAM-e, a nutrient that has powerful mood and  sleep-cycle regulating properties. Because of its ability to increase  the production of neurotransmitters and nerve cell transmission, B12 has also been shown to improve cognitive function.

Ortho Molecular Products Body Goal Fresno, Ca 93710

The Power of Efficacy

 The Power of e is our commitment to efficacy  that produces the highest possible levels of patient wellness. From  raw-material selection, all the way to the finished products we  manufacture, everything we do is guided by the goal of achieving greater  efficacy. We are proud of our 25 year tradition of successfully  combining evidence-based formulations and superior raw ingredients to  develop efficacious supplements that noticeably enhance patient health. 

Formulations That Work

Manufacturing to a Higher Standard

Quality Beyond What's Expected

Formulas developed using the most well-researched and efficacious ingredients.

Quality Beyond What's Expected

Manufacturing to a Higher Standard

Quality Beyond What's Expected

OMP  manufactures their own formulas and controls every step of the process - a rarity in today's industry.

Manufacturing to a Higher Standard

Manufacturing to a Higher Standard

Manufacturing to a Higher Standard

Products are rigorously tested in state-of-the-art in-house laboratories to ensure the purity, strength, and composition. 

These statements have not been evaluated by the Food and Drug Administration. 

This product is not intended to diagnose, treat, cure, or prevent any disease.